Human Pathology (MLTS2202)
BSc, Biochemistry - BCHS
Semester: Second Semester
Level: 200
Year: 2010
UNIVERSITY OF BAMENDA
FACULTY OF SCIENCE
END-OF-SEMESTER EXAMINATIONS
Department: biochemistry and microbiology Course instructors: njie s.m & boyd m.c
Month : June Course code & Number: MLT 202
date : 28/06/2010 Course title: Human Pathology
Time allowed: three hours Credi value: 06
Instructions: Follow the instructions in each section.
SECTION I: 25 marks.
Answer all questions. Note that a sentence should not contain more than 2 lines.
(I) State 2 ways in which the Skin is involved in immunity (2 marks)
(2) Name the groups of cells that are implicated in the non-specific immune response (2 marks)
(3) In 3 sentences, show that the activation of the complement system has lead to inflammation (3mks)
(4) (a) State the location of the class II molecules (0.5mk)
(b) To what major group do the above molecules belong? (0.5mk).
© State the function of the class II molecules (1mk)
(5) In 3 sentences, state why severe skeletal muscle weakness is a characteristic of myasthenia gravis ( 3
mks).
(6) (a) Name the types of immunoglobulins that are found in humans (1mk).
(b) Haemoglobin A has 2 α and 2 β chains. Hence its structure is written as α
2
β
2
. With and γ) in
immunoglobulins and that the heavy chain in IgM is the µ chain. (2 mks)
(7) In 2 sentences, state how the activation of the complement system occurs in the classical pathway (2
mks)
(8) (a) Name the types of immunoglobulin that is implemented in the type I hypersensitivity state (0.5
mk)
(b) In a tabular form, list 3 ways in which the inflammatory exudates differs from normal tissue fluid (3
mks).
(10) Identify the underlined letters in the following statement. “ In the inflammatory disorder called A,
the lumen of the larynx B. This is due to C” (1.5mks)
(11) What event must occur before suppuration takes place? (1mk)
(13) State a difference between the acute and chronic inflammatory responses (1mk)
(14) Name the factors that determine the magnitude of the relative centrifugal force. (1mk).
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