HUMAN PATHOLOGY CA (MLTS2202)
BSc, Biochemistry - BCHS
Semester: Second Semester
Level: 200
Year: 2018
Human pathology MLTS 2202
ACUTE AND CHRONIC INFLAMMATION MCQ
1. What are the 5 cardinal signs of Inflammation?
A. callente, rubarbo, tamar, doll, functloner
B. callente, rubor, tumor, dola, functioner
C. calor, rubor, tumor, dolor, functio Iaesa
D. color, rubarbo, tamar, dolor, functio laesa
2. True or False? Inflammation can occur in dead tissue?A. true B. false
3.
True or false? Changes in blood flow represents the body's first response to Injury. A. true B. false
4. What is the first response of arterioles to Injury?
A. vasoconstriction B, vasodilation C. redness D. edema E. hyperemia
5. Stacking of erythrocytes (RBCs) are known as what?
A. Margination B. Pavementing C. Forming Rolexes D. Rouleaux Formation
6. What Is the name of the phenomenon where WBC's marginate and become attached to the
edge of the endothelium?
A. cementing B. pavementing C, margination D. adhesion
7. True or false? On microscopic examination, finding of Rouleaux Formation of RBC's means
that there is inflammation.A. true B. false
8. True or False? Marginatlon of neutrophils Is the first cellular change of Inflammation.A. true
B. false
9. Active movement of PMN's along a concentration gradient Is known as what?
A. passive diffusion B. chemotaxis C. facilitated diffusion D. chemotactic diffusion
10. What does the term opsonization mean?
A. to make tasty B. to make optimal C. to make foreign D. to make attractive
11. True or false? A PMN encounters and recongnizes a bacterium as foreign by the pseudopods
extending from the surface of the PMN.A. true B. false
12. How does the PMN recognize and attach to the foreign bacteria?
A. Hcg or complement (C3)
B. Immunoglobulins (IgG-A4) or complement (C4)
C. Immunoglobulins (IgG-Fc) or complement (C3)
D. Hcg or complement (C4)
13. True or False? Immunoglobulins (IgG-Fc) and complement (C3) both act as opsonins.A. true
B. false
14. The process by which the cytoplasm of the PMN surrounds the bacteria and encloses it into
an invagination of the cell membrane Is known as what?
A. phagolysosome B. phagolysls C. phagolum D. phagocytosis E. phagophobia
15. True or false? Inside the phagocytic vacuole, the bacteriu, Is killed by bacteriocidal substances
released from the nucleus of the PMN.A. true B. false
16. Dead and dying PMN's admixed with tissue debris form a viscous yellow fluid called what?
A. xanthochromia B. pus C. xanthelasma
17. What are the different types of inflammation?
A. serious, fiber, purulent, ulcerative, chronic and granulomatous
B. serous, fibrinous, purulent, ulcerative, pseudomembranous, chronic and granulomatous
C. serous, purulent, ulcerative, pseudomembranous and chronic
D. serious, fibrionous, pseudomembranous, chronic, and granulomatous
18. Select 2 examples of serous Inflammation?
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A. the skin vesicles caused by Herpes virus B. acute bacterial meningitis C. bread and butte
D. blisters from second degree skin burns
19. True or false? Serous Inflammation Is considered to be the most severe form of
Inflammation.A. true B. false
20. True or false? The serous fluid is readily resorbed without consequences if the cause is eliminated.
A. true B. false
21. What is an Example of fibrinous inflammation
A. serous pleural effusion B. bread and butter pericarditis C. acute bacterial meningitis
D)
Tuberculoma
22. True or false? Fibrinous inflammation is seen in many bacterial infections, such as strep throat or
pneumonia. A. True B. False
23. inflammation is typically caused by pus-forming bacteria such as ____and ____.
A. Pseudomonas Aeruginosa and Staph
B. E. Coli and streptococcus
C. Staph and stenotrophomonas
D. Staph and streptococcus
24. True or False? A localised collection of pus within an organ or tissue is called an Abscess.
A. True B. False
25. True or false? Tuberculoma (TB Abscess) is a type of purulent inflammation.
A. True B. False
26. True or false ? Abscesses heal on their own and do not need to be taken out.
A. true B. False
27. Inflammation of body surfaces or the mucosa of hollow organs may result in a loss of epithelial
linings is known as what type of inflammation?
A. ulcerative inflammation B. Purulent inflammation C. Fibrinous inflammation D.
28. True or false ? An ulcer is defined as a defect involving the epithelium, but may extend into the
deeper connective tissues as well (ie peptic ulcer)
A. True B. False
29. A form of ulcerative inflammation that is combined with fibrinopurulent exudation is known as
what?
A. fibrinous inflammation B. Perulent inflammation C. Ulcerativeinflammation D.
30. Inflammation that lasts a long time and produces extensive tissue destruction and has a tendency to
heal less readily is known as what?
A. acute inflammation B. Ulcerative inflammation C. Chronic inflammation D.
31. Pelvic inflammatory Disease is an example of chronic inflammation. True or false?
A. true B. False
32. PMNs are present in ___ infections whereas mononuclear cells are present in ___ infections. 2
answers are correct.
A. chronic, acute B. Bacterial, viral C. Acute , chronic D. Viral , bacterial
33. what is a special form of chronic inflammation that typically is not preceeded by an acute, PMN-
mediated inflammation?
A. perulent inflammation B. Ulcerative inflammation C. Pseudomembranous inflammation D.
Granulomutous inflammation .
34. True or false? Tuberculosis is the prototype granulomatous disease,as are certain fungal diseases.
A. true B. False
35. True or false? Granulomatous reactions are mediated by macrophages and T-lymphocytes that
acumulate at the site of injury, forming nodules.
a. true b. False
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36. true or false? Epitheloid cells are motile and phagocytic.
A. true B. False
37. In what type of inflammation of epitheloid cells fuse to form multi-nucleated giant cells found on
the rim of the granulomas?
A. purulent inflammation
B. ulcerative inflammation
C. caseating inflammation
D. granulomatous inflammation
E. casserole inflammation
38. True or false? Granulomas destroy tissue and tend to persist for a long time.
A. true B. False
39. Give examples of granulomatous inflammation.
A. TB, chonic cervicitis, and colitis
B. Duodenal ulcer and histoplasma
C. Pericarditis, TB, and peritonitis
D. TB, histoplasma, and coccidiodes
E. tuna noodle casserole and tuberculosis
40. Regarding acute inflammation
a) Initial vasoconstriction is the result of histamine and nitric oxide
b) Stasis occurs due to vasodilatation and the larger caliber of vessels
c) Increased permeability leads to protein depleted plasma leaking into the tissue
d) Initial formation of endothelial gaps lasts for only 15-30 minutes
e) Cytokines (IL-1 and TNF) are responsible for the early permeability
41 .Histamine is involved in acute inflammatory responses and is released from mast cells. Which of
the following statements is incorrect?
a) It is found in blood basophils, platelets and mast cells
b) It causes increased permeability of arterioles
c) It may be released by physical trauma
d) It causes constriction of large vessels
e) It acts on the microcirculation via H1 receptors
42. Complement
a) Proteins are usually stored in an active state in lysosomal molecules
b) Pathway is inhibited by C3 cleavage
c) C3 is the most abundant protein in the complement family
d) Activation by the classical pathway involves microbial surface antigens
e) Cobra venom activates the lectin pathway
43. Regarding mediators of inflammation
a) TNF is a chemokine with chemoattractant properties
b) TNF contributes to cachexia of disease
c) TNF and IL-1 are produced mainly by activated leukocytes
d) The systemic acute phase response is induced by MIP-1 and RANTES chemokines
e) PAF causes vasodilation when expressed at high levels
44. Chronic inflammation is characterized by all of the below except
a) Tissue destruction
b) Angiogenesis
c) Infiltration with neutrophils
d) Fibrosis
e) Increased tissue concentration of lymphocyte
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