Structural Biochemistry (XXXXX)
College of Technology (COLTECH)
Semester: First Semester
Level: 200
Year: 2013
STRUCTURAL BIOCHEMISTRY
Exam 2013/2014
Time Allowed: 3 Hours
Exercise I – Multiple Choice Questions (Check ✔ or Circle ○ the correct answer) ;
Correct answer = +1 mark, wrong answer = -0.5 marks; insert the question paper in the
answer booklet.
1. Palmitoleic acid is a fatty acid with (a) non double bonds; (b) one double bond in
Trans configuration; (c) one double bond in Cis configuration; (d) two double bonds in
Trans configuration.
2. Nutritional polysaccharides are (a) starch and glycogen; starch and chitin; starch
and cellulose; (d) starch and glucose.
3. In lactose, the linkage is (a) α-1-2- linkage; (b) β-1-2 linkage; (c) α-1-4- linkage
(d) β-1-4 linkage.
4. Neutral glycerides are composed of (a) sphingosine and steroids; (b) glycerol and
fatty acids; (c) glycerol and a phosphate group.
5. DNA contains (a) A, G, C, T bases; (b) A, G, C, U bases ; (c) A, T, C, U bases ;
(d) T, G, C, O bases.
6. The Sanger Method permits one to determine (a) the COOH end group; (b) the
NH
2
end group; (c) both end groups; (d) none.
7. Human lipoproteins which carry dietary triglycerides from the intestines to other
tissues are (a) Chylomicrons; (b) VLDL; (c) LDL; (d) HDL.
8. What does the following equation represent? α- D glucose = 112o → + 52.2o →
19oβ-D glucose (a) stereoisomerism; (b) mutarotation; (c) optical isomerism; (d)
epimerization.
9. Cellulose is made up of repeating units of (a) β-1-4- linkages between D glucose
units; (b) β-1-2- linkages between D glucose units; (c) α-1-4- linkages between D glucose
units; (d) α-1-2- linkages between D glucose units.
10. Chitin consists of (a) N-acetyl muramic acid; (b) N-acetyl glucosamine; (c) D
glucose units; (d) N-acetyl muramic acid and N-acetyl glucosamine.
11. Asparagine and glutamine are (a) non polar amino acids; (b) polar amino acids; (c)
negatively charged amino acids; (d) positively charged amino acids.
12. Glycogen in animals is stored in the (a) liver and bile; (b) liver and muscle; (c)
liver and spleen; (d) liver and adipose tissue.
13. Which of the characteristics below applies to the amino acid Glycine? (a)
Optically inactive; (b) hydrophilic, basic and charged; (c) hydrophobic; (d) hydrophilic,
acidic and charged.
14. Which of the following amino acids may be considered a hydrophobic amino acid
at physiological pH levels? (a) Isoleucine; (b) Arginine; (c) Aspartic acid; (d) Threonine.
15. Which of the following amino acids is most compatible with a helical structure?
(a) Tryptophan; (b) Alanine; (c) Leucine; (d) Proline.
THE REPUBLIC OF CAMEROUN
Peace-Work-Fatherland
THE UNIVERSITY OF BAMENDA
COLLEGE OF TECHNOLOGY
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Exercise II – Histidine and Arginine have four ionisable functional groups.
a) Draw the titration equation of Histidine and Arginine.
b) Determine their pK
a
s. (α-COOH = 2.11; α-NH
2
= 9.00; His = 6.30; inside chain
Arg = 12.5).
Exercise III – Use per iodate ions to distinguish furanosides from pyranosides forms.
Exercise IV – Match these molecules with their biological roles.
Molecules Roles
Answers here with
letters and numbers
a) Haemoglobin
1) Carbohydrate storage In
animals
b) Glycogen
2) Necessary for movements
c) Chymotrysin
3) Structural component of
plant cell walls
d) Antibodies
4) Transports oxygen in higher
plants
e) Albumin
5) Carbohydrate storage in
plants
f) Starch
6) Biological catalyst
g) Actin and myosin
7) Specialized cells of the
immune system
h) Chitin
a) Nutrient protein
Exercise V – Draw the structure of 1-myistic, 2-palmatoleic and 3-stearyl phosphor-
glycerol.
Give the product of the following phospholipases and justify your answer.
a. Phospholipase A
2
b. Phospholipase C
c. Phospholipase D
d. Phospholipase A
1
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